Please inform your doctor about your medical history, especially if you have a history or family history of psychiatric disorders (e.g., bipolar/manic-depressive disorder), history or family history of suicide attempts, glaucoma, prostate problems, decreased urine output, thyroid disease, breathing problems, seizure problems, alcohol use, heart disease, liver or kidney disease, as well as any drug allergies.

Moreover, tell your doctor about the medicines you take, especially if you take any of the following: clonidine, guanadrel, guanethidine, MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), cimetidine, SSRIs (e.g., fluoxetine, sertraline), warfarin, carbamazepine, certain diet pills (e.g., phentermine), adrenaline-type drugs (e.g., dopamine, ephedrine, epinephrine, pseudoephedrine, phenylephrine, isoproterenol - some of which may be found in cough and cold or asthma products), narcotic pain medications (e.g., codeine), cisapride, St John's wort, heart rhythm drugs (e.g., quinidine, flecainide, propafenone), phenothiazines (e.g., Chlorpromazine®), any other prescription or nonprescription drugs you take.

Amoxapine may increase heart rate and stress on the heart. It may be dangerous for people with cardiovascular disease, especially those who have recently had a heart attack, to take this drug or other antidepressants in the same pharmacological class. In rare cases in which patients with cardiovascular disease must receive amoxapine, they should be monitored closely for cardiac rhythm disturbances and signs of cardiac stress or damage.

Use caution when engaging in tasks requiring alertness such as driving or operating machinery.

Additionally, you should limit alcohol consumption as it may increase the drowsiness and dizziness effects of this drug.

Limit exposure to hot weather as it may lead to heat stroke.

Caution is advised when using this drug in the elderly, because they may be more sensitive to the effects of the drug (e.g., confusion may occur or worsen).

This drug should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor. So too, this drug may be excreted into breast milk. The effects on the infant are not known at this time. Consult your doctor before breast-feeding.

FDA Information

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Other uses for this medicine

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In case of an emergency/overdose